Diagnostics

Ultrasound examination

Examination evaluates the shape and size of the uterus as well as the height of the uterine lining. It tracks the growth of follicles in the ovaries at different stages of the menstrual cycle, the presence of cysts and any pathological formations in the lower pelvic area.

Hormonal profile testing

This examination is conducted using a blood sample and provides information about the condition of the ovaries and their ability to generate mature eggs. The blood sample is taken on the second to fourth day of the menstrual cycle. The levels of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) are measured. The level of anti-Müllerian hormone (AMH), which informs about the level of ovarian reserve, can also be measured. Prolactin (PRL) and thyroid-stimulating hormone (TSH) levels are also a standard part of hormonal profiling.

Examination of the fallopian tube patency

Outpatient examination of the fallopian tube patency and uterine shape

HyCoSy (Hysterosalpingo-contrast Sonography) is an examination of the patency of the fallopian tubes by ultrasound using a contrast agent. Compared to hysterosalpingography (HSG – an X-ray examination), it has the advantage that the patient is not exposed to radiation during the examination and the examination is better tolerated by the patient.

Endoscope examination methods

Diagnostic hysteroscopy

Hysteroscopy is an endoscopic examination of the uterine cavity that enables to visualize the anatomical conditions of the uterine cavity and the physician takes a sample of the uterine lining for histological examination. During hysteroscopy, unwanted formations such as polyps can also be removed. This examination is usually performed under general anaesthesia.

Diagnostic laparoscopy

This surgical procedure is not performed in our facility, but it is possible to request this examination in one of our partner clinics. It is used for a detailed examination of the pelvic cavity. It can also be used to test the patency of the fallopian tubes, to treat cysts or adhesions.

Sperm analysis

A sperm analysis is a laboratory evaluation of sperm quality. The volume of the ejaculate, the quantity of sperm, their motility and morphology (shape of the heads, necks and flagella) are evaluated. The semen sample is obtained in the collection room at our clinic. By prior arrangement it is possible to bring a semen sample from home. If the sperm analysis is to be reliable, it should be done after 2-3 days of sexual abstinence.

How to proceed in case of poor sperm analysis results?

If the sperm analysis shows an abnormality, it is advisable to repeat the test after two to three months. This recommendation is based on the duration of spermatogenesis – the development of sperm, which takes about 75 days. It is important to note that a sperm analysis cannot be concluded from a single test. Spermatogenesis is a dynamic and variable process that is influenced by number of factors (acute illness, lifestyle changes, environmental changes, etc.). In order to have a realistic picture of your spermatogenesis, we recommend that you carry out this examination two times in a row, always two to three months apart.

DNA fragmentation in sperm

One of the conditions for successful fertilisation of an egg is intact nuclear DNA, which is stored in the sperm head. DNA fragmentation is described as the breakage of one or both DNA strands. In case of such damage to the genetic information of the sperm, the development of the embryo can be impaired, which may be a direct cause of infertility treatment failure or repeated spontaneous abortions. Thus, sperm DNA fragmentation testing is an important diagnostic tool in assisted reproduction for repeatedly unsuccessful treatment of infertile couples.

In good quality ejaculate, the proportion of sperm with fragmented DNA is less than 15 %. If 15–30 % of sperm has fragmented DNA, it is considered a slightly elevated value, and if it is more than 30 %, it is considered a high value. For such results, we recommend patients to choose the MACS (magnetic separation of damaged sperm) method for IVF to prepare sperm before fertilization of eggs.

Infertility treatment

IUI

INTRAUTERINE INSEMINATION

IVF

IN VITRO FERTILIZATION WITH OWN OOCYTES

DIVF

IVF WITH DONATED EGGS

FET (FROZEN EMBRYO TRANSFER)

TRANSFER OF EMBRYO FROZEN DURING PREVIOUS TREATMENT

Special laboratory methods

METHODS OF FERTILIZATION

PGT

EMBRYOGLUE

CRYOPRESERVATION

EXTENDED CULTIVATION

TIME-LAPSE

SPERM MOBIL

Other care provided

Genetic counselling

Clinical genetics covers the diagnostics and prevention of diseases with a hereditary component. We focus mainly on diseases and conditions affecting fertility and leading to birth defects. During the genetic consultation, we also pay attention to the occurrence of hereditary sensory defects and cancers in the family.

Indications for genetic testing:
  • Congenital defect or a disease with possible hereditary component in the family.
  • Birth of a child with a congenital defect.
  • Infertility, repeated spontaneous abortions, stillbirth.
  • Pregnancy planning after cancer treatment.
  • Repeated or frequent occurrence of cancer in the family.
What happens during a genetic consultation?

During the consultation, the physician (clinical geneticist) finds out details about the health of the patient and his/her family members (medical history), based on which he/she creates a three-generational family tree (genealogy), evaluates the results of cytogenetic examination of chromosomes and molecular genetic examination (congenital changes – gene mutations) and based on the results recommends further genetic testing, if necessary.

Immunological testing

The aim of immunological testing in reproductive medicine is to diagnose the possible cause of immunological imbalance. Laboratory tests can reveal changes in both humoral and cellular immunity. Considering the way of necessary treatment, it is always advisable to consult with our in-house reproductive immunologist.

When is the immunological testing performed?
  • In couples with an unexplained cause of infertility.
  • In women after repeated miscarriages.
  • In couples with repeated IVF failure.
  • In couples with a diagnosed immune disorder – in case of known autoimmune disease.

FAQ

At our clinic, we always strive to make our patients happy. Our knowledgeable physicians will recommend the best treatment based on your medical history and guide you through the entire process. A friendly team of nurses and midwives will always be on hand to help you.

The first consultation, and every subsequent one, is free of charge, so do not hesitate to make an appointment, our physicians are looking forward to meeting you.

A referral from a gynaecologist or another physician is not necessary. However, if you have undergone any relevant examinations bring the results with you.

Ideally, both partners should attend the first consultation, but this is not a requirement, so feel free to come alone.

According to current legislation in the Czech Republic, on the day of embryo transfer or insemination, the woman must not be older than 48 years + 364 days. After the age of 49, the treatment cannot be performed.

Do you have different question?

This is the website of IVF Clinic a.s., which belongs to the FutureLife group, with its registered office at Olomouc, Nová Ulice, Horní lán 1328/6, ID: 29358914, registered in the commercial register kept at the Regional Court in Ostrava, section B, insert 10467. The company ceased to be a member of the SYNBIOL concern with effect from 22 May 2021, based on the notification of the managing person of the concern – the company SynBiol, a.s., IČO 26014343. The latter informed that the existence of the concern is no longer given as of that date, with the fact that the persons directly or indirectly controlled will no longer be subject to unified management in the sense of §79 paragraph 1 of the Act on Business Corporations.

Address

IVF Clinic, a. s.
Horní lán 1328/6,
Nová ulice,
779 00 Olomouc

Contact

+420 588 884 180
info@ivfclinic.cz

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